Everybody hates you when you’re the best, and everybody hates you when you’re the worst.

I went from buying my own condominium and a car for myself when I was 17 on ‘The Facts of Life’ to not being able to pay my rent. I was at the unemployment office...

You can’t regulate what these kids are being exposed to on the Internet. It’s so way out of control. All you can do is just try to talk to your own kids.

The thing about women playing boys is that we’re not going to age, and we’re not going to go through puberty in the middle of a long-running series.

Before ‘Lucky Louie,’ nobody would ever cast me to play a mom or a wife; nobody ever saw me in that role, which is weird, since that’s who I really am.

I don’t think I have a demographic. I was at Comic-Con in San Diego recently, and I was doing a signing, and my line was all military guys, young girls, housewives and guys in wheelchairs....

One of the things I learned in animation is that you never, ever want to start doing a voice that you can’t sustain for four straight hours.

My roles in the ’80s were, like, gender dysphoric. I wasn’t pretty, I wasn’t this, I wasn’t that. And I am kind of butchy, you know. That’s just my thing.