When people are facing a severe illness or a major surgery, that may be one of the most significant opportunities for spiritual transformation that they will encounter.

In Sweden, only exceptional actresses get major film parts.

The major mistake people pursue in decision making is to surround themselves with negatively minded people. People who are going nowhere will never take you anywhere; people who are going everywhere can take you somewhere.

There are scientists all around the world looking for the genes responsible for bipolar illness and major depression.

There are no major cities I haven’t been in – at least once. I’d be just as happy not to go out of town for a couple of months and play with toys.

My high school coach was Ray O’Conner. He has coached a lot of players that have signed professional contracts, and many of those have gone on to play in the major leagues.

As a major contemporary composer, Madonna should not let the eye dictate to the ear.

Every major accomplishment in a man’s life requires a major level of commitment.

One major factor that will prevent your dreams from becoming nightmares is learning to vacate your spectators’ seat and then taking steps towards the players’ bench! You’ve got to play to win!

There has not yet been a major ground offensive battle… There are, we know, negotiations going on between the opposition forces and the Taliban leadership for surrender.

Although it is still important to develop an HIV vaccine, we have significant tools already at our disposal that can make a major impact on the trajectory of this epidemic.

Constant attention by a good nurse may be just as important as a major operation by a surgeon.

You have nothing coming into a major metropolitan area to relocate or locate your business and employees. And you can go across the country and you’ll see that.

You wouldn’t want to be called a sell-out by selling a product. Selling out was frowned on, whereas now you can major in it at business school.

Over the years your bodies become walking autobiographies, telling friends and strangers alike of the minor and major stresses of your lives.